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From Biomedical Insights to Decisions: A Future-Ready Playbook for Medical Science Liaisons

December 1, 2025
Author(s): Sandra F. Gomes, MSc

Medical Affairs is moving from “science conduit” to decision partner - a role that asks Medical Science Liaisons (MSLs) to spot real-world signals, turn them into timely actions, and explain numbers so clinicians and patients actually change what they do next (1,2). The good news: you do not need a data lake or a PhD in artificial intelligence (AI) to start; what you need is a … [Read more...]

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What Makes an MSL Truly Exceptional? Lessons From the Best MSLs Around the Globe

December 1, 2025
Author(s): Víctor Sastre, MS, MSL-BC

Lessons from the Best MSLs Around the Globe As a member of the judging panel for the Medical Science Liaison Society (MSLS) Awards, I had the opportunity to thoroughly review and evaluate the submissions from candidates aspiring to be recognized among the best MSLs worldwide. Based on this experience, the present document analyzes a series of testimonies and perspectives … [Read more...]

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Applied Neuroscience to the MSL Role: How to Train the Brain to Influence With Integrity

December 1, 2025
Author(s): Martina Riosalido, MS

Introduction Imagine this: you walk into a meeting with a leading Key Opinion Leader (KOL). This person barely looks up from his phone, nods while you speak, and leaves you wondering—did my message even land? The very next day, you’re facing a player who insists on cost-effectiveness data, followed by a Digital Opinion Leader DOL asking for a visual summary he can share on … [Read more...]

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From Transaction to Interaction: Leveraging Commercial Acumen for Deeper Scientific Exchange

December 1, 2025
Author(s): Fady Morcos

For many of us who transition into the Medical Science Liaison (MSL) role from commercial backgrounds, there’s a moment of deliberate recalibration. We learn to set aside the language of “sales targets” and “prescription volume” and embrace the principles of non-promotional, scientific exchange. This is not just a necessary shift; it is the very foundation of our credibility … [Read more...]

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Highly Effective Use of a Medical Affairs Team With Medical Science Liaison-Delivered Education: The SMART-MSL Study

December 1, 2025
Author(s): Janelle O. Poyant, PharmD, BCCCP, Jacqueline Chaben, BSN, PharmD, BCCP, Stacy Revelle, PharmD, BCPS, BCEMP, Victor Rivera, PharmD, Brianne Ritchie, PharmD, MBA, Hijrah El-Sabae, PharmD, Doug Wylie, PharmD, BCCCP, Steven Ness, DO, Nouran Salem, PharmD, MBA, BCCCP and Sheena Merwine, PharmD

Introduction Cangrelor is an intravenous P2Y12 inhibitor indicated as an adjunct to percutaneous coronary intervention (PCI) for reducing the risk of periprocedural myocardial infarction (MI), repeat coronary revascularization, and stent thrombosis. [1] Cangrelor provides immediate platelet inhibition (onset within 2 minutes following administration of a 30 mcg/kg IV bolus, … [Read more...]

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The Clinician’s Compass: Why Those Who Care at the Bedside Lead Best in Medical Science Liaison Roles

December 1, 2025
Author(s): Tracy R. Wilson, DNP, FNP-C

Disclaimer: This article was developed with the assistance of generative AI tools. Abstract Clinicians—nurse practitioners, physician associates, pharmacists, and physicians—are uniquely equipped to lead in Medical Science Liaison (MSL) roles because they bring the human experience of care into the science of communication. This editorial explores how the clinical mindset, … [Read more...]

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Integrating HEOR and Real World Evidence: The Expanding Strategic Function of Medical Science Liaisons

December 1, 2025
Author(s): Nadia Najam, MBBS

In today’s data-driven healthcare landscape, the value of a therapy extends far beyond its efficacy in clinical trials. Payers, policymakers, and healthcare providers increasingly demand evidence that demonstrates real-world value. This shift has placed Health Economics and Outcomes Research (HEOR) and Real-World Evidence (RWE) at the heart of medical strategy. We explore … [Read more...]

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The Future of Personalized, Measurable MSL Engagement

December 1, 2025
Author(s): Susan Giacalone, MSN, BCMAS, BC-MSL

Introduction Medical Science Liaisons (MSLs) have established themselves as trusted partners to healthcare professionals (HCPs), with 58% of HCPs rating MSL interactions as more valuable than those with sales representatives—and an additional 18% rating them as much more valuable. However, trust in itself is insufficient as MSLs encounter growing demands to provide … [Read more...]

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The Role of Medical Science Liaisons in Medical Affairs Booth Support at Regional Conferences

December 1, 2025
Author(s): Anna Frank, PA-C

Purpose and Context Regional scientific conferences serve as accessible, cost-effective venues for fostering meaningful scientific exchange among healthcare professionals (HCPs). When Medical Science Liaisons (MSLs) participate in Medical Affairs booths at these events, they play a pivotal role in building local connections, facilitating evidence-based conversations, and … [Read more...]

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From Sales Rep to MSL, a Journey of Evolution and Discovery

December 1, 2025
Author(s): Antonio Castiglia, MSc

The importance of being E.. xplorative! The transition from pharmaceutical sales to Medical Science Liaison represents more than a career move; it’s a transformation that demands curiosity, dedication, and the courage to step into an undefined role. My journey began when the company I was working for at that time decided to create its first MSL positions, selecting specialty … [Read more...]

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Five Bioethical Foundations for Good Clinical Research & Practice

December 1, 2025
Author(s): Dallas V. Mullins II, MSc, MAT

INTRODUCTION: In these times of rapid discovery, it is vital to remember five bioethical foundations undergirding all beneficial medical research. These foundations (summarized by the acronym BNAIJ) are beneficence, nonmaleficence, autonomy, informed consent/assent, and justice. Others have written more detailed explanations of these foundations. However, this primer is … [Read more...]

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Reducing Diagnostic Delays in Rare Diseases: The MSL’s Role in Closing Knowledge Gaps

December 1, 2025
Author(s): Rohan Zaveri, PharmD

Diagnostic delay is one of the biggest challenges in managing rare diseases. For example, narcolepsy patients often wait between 8 to 15 years from the onset of symptoms to receiving a proper diagnosis. This delay can severely disrupt their education, jobs, and mental health (Carter LP et al., Postgrad Med 2014; 126(3): 216-24). Closing this gap requires more than just … [Read more...]

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Trust in Government Agencies Falters: MSLs Can Fill Credibility Gap and Combat Misinformation

November 28, 2025
Author(s): Justin O'Rourke, MA, MBA

For decades, agencies under the U.S. Department of Health and Human Services (HHS) were regarded as the gold standard for medical and scientific guidance. Healthcare professionals (HCPs) trusted these agencies to provide reliable, evidence-based recommendations that shaped clinical practice standards and public health interventions. As federal health agencies face mounting … [Read more...]

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The Science of Culture: How Values-Driven Leadership Improves Results, Retention, and Reputation in Medical Affairs

November 28, 2025
Author(s): John Waid

The Missing Ingredient in Scientific Success In a profession that thrives on evidence, reproducibility, and rigor, one variable remains under-measured but over-influential: culture. For Medical Science Liaison (MSL) teams and broader life-science organizations, culture is not a soft metric — it’s the hidden force that determines how knowledge flows, how people behave under … [Read more...]

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